Tottenham received a major boost before kickoff as key defenders Cristian Romero and Micky van de Ven returned to the starting lineup together for the first time since December. Despite dominating possession early on, Spurs struggled to create clear chances until AZ Alkmaar's defensive lapse in the 26th minute.
Wouter Goes' attempted clearance was blocked by Son Heung-min, allowing Dominic Solanke to set up Wilson Odobert, who curled the ball into the net from 12 yards to break the deadlock.
Just moments into the second half, Tottenham doubled their lead and took control of the tie for the first time. James Maddison, eager to impress new England manager Thomas Tuchel ahead of his squad announcement, calmly slotted home from a Son assist.
However, their advantage was short-lived as a mix-up between Odobert and Lucas Bergvall gifted Peer Koopmeiners the ball, and the AZ midfielder powered in a strike to reignite his team's hopes.
Spurs responded strongly and sealed their victory with a well-worked goal in the 74th minute. Maddison's clever turn opened up space before he played in Djed Spence on the left.
Spence delivered a precise cross that Solanke flicked on, allowing Odobert to tap in at the far post and secure Tottenham's progression in the competition.
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